"Based on Patrick DeWitt's novel, 'The Sisters Brothers' revolves around the colourfully named gold prospector Hermann Kermit Warm, who's being pursued across 1000 miles of 1850s Oregon desert to San Francisco by the notorious assassins Eli and Charlie Sisters. Except Eli is having a personal crisis and beginning to doubt the longevity of his chosen career. And Hermann might have a better offer." (IMDb)

"Charlie and Eli Sisters live in a wild and hostile world. They have blood on their hands: the blood of criminals and innocent people alike. They have no scruples about killing. It's their job. Charlie, the younger brother, was born to kill. Eli, however, dreams of living a normal life. They are hired by the Commodore to find and kill a man. From Oregon to California, a ruthless hunt begins, an initiatory journey that will test this insane bond between the two brothers. A path that leads to their humanity?" (La Biennale di Venezia)